Dolly dead...

[Andonyx]

Dolly the sheep, the world's first cloned mammal has passed according to a breaking news report on MSNBC.

There is no article yet, but I will add a link as it becomes available.

Edited to Add Links:

http://www.startribune.com/stories/1556/3654206.html

http://www.ananova.com/news/story/sm_750864.html

http://www.timesdaily.com/apps/pbcs.dll/article?Date=20030214&Category=API&ArtNo=302140844&Ref=AR

[Goshawk]

They're going to stuff her and put her on display. Not quite sure why that bothers me...Maybe because after hearing about her for so long, I feel like I know her personally...



http://www.cnn.com/2003/WORLD/europe/02/14/cloned.dolly.dies/

[Smalso]

Thanks for the info. I didn't know Dolly had punted the pail. I remember hearing a couple of years ago that she was showing signs of premature aging, leading to speculation about whether the cells of the host--in this case a six-year-old sheep--might be preprogrammed with the age of the host. Interesting.

[Andonyx]

Originally posted by Smalso
Thanks for the info. I didn't know Dolly had punted the pail. I remember hearing a couple of years ago that she was showing signs of premature aging, leading to speculation about whether the cells of the host--in this case a six-year-old sheep--might be preprogrammed with the age of the host. Interesting.

I may be mistaken but I believe that's what began the discussion of the length of telomeres affecting the apparent age of the individual. And as such, the DNA might be intact but the telomeres would have the length of an older person / ovine.

[Goshawk]

Actually, she didn't punt the pail by herself--they euthanized her. She had a "progressive lung disease".

[Soapy Sam]

GOOD GOD MAN! I THOUGHT YOU MEANT DOLLY PARTON!

Quite gave me a bad turn.

[Always Free]

Originally posted by Smalso
Thanks for the info. I didn't know Dolly had punted the pail. I remember hearing a couple of years ago that she was showing signs of premature aging, leading to speculation about whether the cells of the host--in this case a six-year-old sheep--might be preprogrammed with the age of the host. Interesting.
This is good news. This may be the nails in the cloning coffin.:mad:

[The Central Scrutinizer]

Originally posted by Always Free

This is good news. This may be the nails in the cloning coffin.:mad:

You're joking, right???

[Andonyx]

Originally posted by The Central Scrutinizer


You're joking, right???

Well, wait there is a large cavernous disconnect between cloning and stem cell research that I wish the legislative bodies would make more clear.

Human cloning is quite obviously not ready for primetime, but the techniques and information we can get from its principles should not be hindered.

Putting a permanent kaibosh on cloning is a bit shortsighted, but hopefully we can conclude from this episode that anything like, say a raelian claim to human cloning is grossly negligent.

[Always Free]

Originally posted by The Central Scrutinizer


You're joking, right???

CS, you don't have future plans to clone yourself do you?LOL!

I think we can all live without it, we have so far. I do however agree with stem cell research, even growing bodily organs etc. But to clone for duplication of an original, uniqie being---no way!!
:mad:

Geez, I know I've been hanging around this board too long! A few years ago, I probably would have thought Dolly Parton from the thread title. Now, it didn't even occur to me until I saw the post!

[Shane Costello]

Originally posted by Always Free:
I think we can all live without it, we have so far. I do however agree with stem cell research, even growing bodily organs etc. But to clone for duplication of an original, uniqie being---no way!! :mad:

Well no-one seriously advocates reproductive cloning of humans. However there are some pretty interesting things in the pipeline that utilise cloned animals, so I wouldn't like to dismiss the technology just yet.

In terms of reproductive cloning I would have thought the old fashioned way of making a human was much more fun than using molecular biology techniques (I've experiemce of both, believe me!) ;) :D.

For what it's worth, I believe the advances in adult stem cell research will probably make embryonic stem cell research obsolete.

[Smalso]

Originally posted by Always Free

This is good news. This may be the nails in the cloning coffin.:mad:

Nah. Just another problem to be overcome.

[Soapy Sam]

Denise- you don't have my additional male sexual motivation. If ever there was a Dolly who should be cloned it has to be the one in Nashville!

[hammegk]

Originally posted by Soapy Sam
Denise- you don't have my additional male sexual motivation. If ever there was a Dolly who should be cloned it has to be the one in Nashville!

Will the bags of silicon also be cloned????

[gmol]

Originally posted by Always Free


CS, you don't have future plans to clone yourself do you?LOL!

I think we can all live without it, we have so far. I do however agree with stem cell research, even growing bodily organs etc. But to clone for duplication of an original, uniqie being---no way!!
:mad:

Yeah duplication is just downright evil!
We should burn one of every pair of identical twins that was ever concieved!

[arcticpenguin]

I hope they saved a few of Dolly the sheep's cells so they can clone her.

[Soapy Sam]

Hammegk, you immaterialist scoundrel! How dare you denigrate the fairest specimen of American Womanhood? Choose your weapons, sir!

[richardm]

Originally posted by Smalso
I remember hearing a couple of years ago that she was showing signs of premature aging, leading to speculation about whether the cells of the host--in this case a six-year-old sheep--might be preprogrammed with the age of the host. Interesting.

IIRC she began to develop arthritis-type symptoms, which are more commonly found in older sheep. What many of the reports didn't mention was that while it's more common in older sheep, it's far from unknown in younger sheep too. One of the problems with a sample of one, I suppose, is that you can't deduce anything much about trends.

According to the radio, there are quite large numbers of cloned sheep around the world now, so we should be getting towards some answers.

[Mr. Turquoise]

Originally posted by arcticpenguin
I hope they saved a few of Dolly the sheep's cells so they can clone her.

Me too. It would be very interesting how long that one lived. I also hope that further examination of the carcass sheds some light into whether she really was aging prematurely.

Mr. Turquoise

[Smalso]

Originally posted by richardm


IIRC she began to develop arthritis-type symptoms, which are more commonly found in older sheep. What many of the reports didn't mention was that while it's more common in older sheep, it's far from unknown in younger sheep too. One of the problems with a sample of one, I suppose, is that you can't deduce anything much about trends.

According to the radio, there are quite large numbers of cloned sheep around the world now, so we should be getting towards some answers.

I, for one, will be looking forward to it.

[hammegk]

Originally posted by Soapy Sam
Hammegk, you immaterialist scoundrel! How dare you denigrate the fairest specimen of American Womanhood? Choose your weapons, sir!

In view of the realities involved, a duel with 20" plastic dildos in lieu of epees.

[Soapy Sam]

You think I would turn my back and take 5 paces away from a philosopher with a 20"dildo?

[neutrino_cannon]

Originally posted by arcticpenguin
I hope they saved a few of Dolly the sheep's cells so they can clone her.


As I recall the cells that were used to spawn Dolly were derived from mammery cells during a certain point in pregnancy, which for some reason made them easier to clone.

Dolly mk ii?

[neutrino_cannon]

Originally posted by Always Free


CS, you don't have future plans to clone yourself do you?LOL!

I think we can all live without it, we have so far. I do however agree with stem cell research, even growing bodily organs etc. But to clone for duplication of an original, uniqie being---no way!!
:mad:

For various reasons (difference in age, mitochondrial DNA, determining factor egg proteins etc) a clone is hardly a replica of the original. I do agree that it would be grossly negligent to clone a human given the current level of technology, not to mention pointless and expensive, but there is no reason to say cloning is evil. Evil is a social construct, cloning is a (silly) way to make twins. There is no more overlap here than would be normaly considered in making children, except for the technical complications of cloning itself.




A duel with dildos? I'll keep my mg-42 thank you.

[fishbob]

Originally posted by Always Free

I think we can all live without it, we have so far. I do however agree with stem cell research, even growing bodily organs etc. But to clone for duplication of an original, uniqie being---no way!!

----------------------------------
If you donated a couple of extra cells today and had them cloned, your clone would be:

1) 15 to 75 years younger than you are
2) raised on a different diet than you were
3) exposed to a changed culture
4) exposed to a different environment
5) subjected to different experiences
6) different education

This technology can start an individual with the same set of plans a a previous individual - as happens with identical twins already.

Cloning is not capable of duplicating an original, unique being. For that, we are going to need some new developments from the Xerox Corporation.

[richardm]

Originally posted by neutrino_cannon



As I recall the cells that were used to spawn Dolly were derived from mammery cells



Hey.... Is that why she was called Dolly? How could I have missed that gag :D