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Lucifuge Rofocale
18th April 2009, 12:18 PM
The new miraculuos pill, claims to be studied in 5230 clinical trials, developed by actafarma with help of the Scientific investigations Superior Council of Spain (I don't know what is this) ..... but is sold as dietary suplement :confused::hb:


Info (In spanish only AFAICS):

www.revidox.com (http://www.revidox.com)

paximperium
18th April 2009, 12:23 PM
Since I don't read spanish...what the heck is it?

Lucifuge Rofocale
18th April 2009, 12:27 PM
Since I don't read spanish...what the heck is it?
http://www.typicallyspanish.com/news/publish/article_20951.shtml
http://www.mediterraneandiet.com/2009/04/18/sirtuin/
http://www.barcelonareporter.com/index.php?/news/comments/ageing_process_cut_in_half_but_watch_out_for_the_l iver/
http://www.dailynews.rs/news/

Ageing process cut in half but watch out for the liver.
These scientists have found a secret ingredient which is abundant in Spain. ‘Wine’

Source: Barcelona Reporter Section: Health (http://www.barcelonareporter.com/index.php?/news/C22/)
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Ageing process cut in half but watch out for the liver.

Spanish scientists have been working on a pill that will reduce the ageing process in humans.

These scientists have found a secret ingredient which is abundant in Spain. ‘Wine’.

To benefit from the ageing process, a person would need to drink 45 bottles of wine. This would inevitably destroy the liver.

What the scientists have produced is a pill which has been synthesised into 8 milligrams of resveratrol. They subject the grapes to ultraviolet light for some seconds, which is the key ingredient for the pill.
The pill is produced and is in the form Revidox.

The scientists state that the result is cutting the ageing process in hal

paximperium
18th April 2009, 12:37 PM
Ugh, not resveratrol again.

Alright resveratrol has some pretty good evidence that it does some good things as an anti-oxidant, platlet inhibitor and even some data for cancer therapy. But like any other product that is being researched, the CAM proponents will jump on it and claim that it is some magical compound.

What does it even mean that "aging is cut in half"? Does a person live twice as long?

PS: Many but not all supplements are woo. Omega-3 Fatty acids and Niacin are supplements but are very useful for the treatment if cholesterol and heart disease.

T.A.M.
18th April 2009, 06:04 PM
yah, if you don't mind the flushing!!!

TAM:)

paximperium
18th April 2009, 09:24 PM
yah, if you don't mind the flushing!!!

TAM:)
I like my niacin...it just feels like I'm fire for 10minutes.

casebro
18th April 2009, 10:40 PM
Are there any in-vivo studies of resveratrol, or are all those advantages only in vitro?

Didn't I also hear that any alcohol has those good effects of red wine? I'll drink to that!

And Niaspan sure helped my cholesterol numbers. Though an afternoon dose gives me heart burn. And I do feel the flush for just a few minutes, about 20-30 minuters after the morning dose.

T.A.M.
19th April 2009, 06:22 AM
I like my niacin...it just feels like I'm fire for 10minutes.

OT:

Actually Niacin is a very good "drug". If you can stand the flushing, and monitor your LFTs, it is one of the few treatments that has been shown to increase your HDL, as well as lower your LDL.

TAM:)

ziztur
29th April 2009, 05:19 PM
I wrote this (on my blog) awhile ago when I got a RezV spam in my inbox:

Today I got some new spam in my inbox: this time, it's for RezV, a supplement pill containing resveratrol, a substance largely touted as being found in red wine.

The body of the e-mails says, in big letters: "discover how YOU can live to be 150"

When you go to their website, you're greeted with a video of an Oprah (Pseudoscience Queen) segment, where a very hyperactive dude with creepy eyebrows hawks a bunch of green horse pills that apparently contains a concentration of resveratrol. You'll also find the logos of USA Today, NBC, CNN, Discovery Channel, Fox News, CBS, People, NBC (again?), Reader's Digest, Cosmopolitan, and PBS.

Their moneyback guarantee:

MONEY BACK GUARANTEE
We are so confident that you will love RezV that we are not only going to give you a free trial period for the full month supply, but a RISK FREE 14 day money back guarantee. You will have 14 days from the date of your order to evaluate the product. If you decide you are unhappy with the product, cancel at any time during that 14 day period and pay nothing except shipping and handling. If you do not cancel, you will receive every 30 days a fresh one-month supply of RezV as part of our delivery program, for which you will be automatically billed $87.97 per month (a 21% savings off the regular price!) There are no obligations, and you can
cancel at anytime via our customer support line.

Since when does "RISK FREE" mean that if you don't cancel within 14 days of placing your order (which means that if it takes a week to get from their warehouse to your doorstep, you have 7 days to try it) you'll be automatically billed $90+ per month. It seems to me that purchasing your "free trial" comes with the risk of your credit card being charged if you don't hop up and call the customer service line - and you know that they are going to try to convince you to keep using their product.

Oh come on Ziztur, you say, they can't really mean that the 14 day trial period begins from the moment you order it, can they? Yep, it says as much under "Terms & Conditions":

14 DAY TRIAL PERIOD INCLUDES SHIPPING AND TRANSIT TIME

Some of the "testimonials" on the website are just frightening. Take "Kelly Ann's" Testimonial:

My muscle tone is so much more firm, especially around my waist area, without actually having to work out.

Oh ****** She's had a brain injury! Abnormal muscle tone is a sign of serious central nervous system dysfunction. I have to recommended that she stop taking her placebopills and see a real doctor.

Studies on humans have shown that even in doses much higher than the pull form offered (5 grams vs 20-200mg, depending on whose hawking it) did... nothing. The headline-grabbing Harvard study, published in 2006, showed that obese, middle aged mice who had resveratrol added to their high-calorie, high-fat diet became healthier and lived longer. A similar study, published later by the same researchers, showed that middle-aged healthy mice fed regular diets did not live longer or have increased health when given resveratrol vs. a placebo. [1] There are no studies showing that resveratrol has any positive affect on humans, though there are studies showing that it increased the lifespan of some fish, a fruit fly, and a type of worm. Yet before appropriate studies can be conducted on humans, countless pill-peddling companies are selling their supplements for unforgivably expensive prices.

It's funny that all of the websites and videos show people drinking red wine, or show pictures of red wine, and talk about how the compound is found in red wine, but most (all?) resveratrol supplements are not made from wine or grapes (or peanuts, which also contains resveratrol) but japanese knotweed. I guess it doesn't sound quite as enticing and sophisticated to say your supplement is derived from Japanese knotweed as it does to say it's from red wine.

All of this red-wine-makes-you-healthier stuff comes from the idea of the French Paradox - wherein the French supposedly consume a diet higher in saturated fats, but have less heart disease than Americans - a 60 Minutes show in 1991 suggested that this was due to the French's consumption or red wine. Even the Wikipedia article on the subject suggests that the French Paradox is an overblown case of misplaced causation. The idea has been debunked with research by ... ironically ... some researchers in France. The French Paradox has also been debunked by statisticians - but this doesn't stop weight-loss companies from continuing to use it to their advantage.

1. Schard, D. Nutrition Action Health Letter; Mar2009, Vol. 36 Issue 2, p9-9, 3/5p, 1 color



After I posted this, someone spammed my blog, telling me how amazing Resveratrol is and linking me to his website with a bunch of journaled studies - none of which actually used humans. Mice and test-tubes, sigh.

Gord_in_Toronto
29th April 2009, 07:12 PM
<snip>

After I posted this, someone spammed my blog, telling me how amazing Resveratrol is and linking me to his website with a bunch of journaled studies - none of which actually used humans. Mice and test-tubes, sigh.

Well, I for one, could use some longer lasting test tubes. You know what those things cost these days? ;)

Soapy Sam
30th April 2009, 04:01 AM
The scientists state that the result is cutting the ageing process in hal

Good grief!

Has anyone told him?