Fecal transplant may help prediabetes symptoms

[commandlinegamer]

http://www.medpagetoday.com/MeetingCoverage/EASD/22352

Sounds promising, but given the enormous amount of bugs in our intestines, are we at a stage where we can definitively say which are good or bad? Do we still understand more about the surface of the moon, than our own guts?

[Vorticity]

I'm afraid that this thread isn'tgoing to get much further than the first two words of the title.

[Starthinker]

I predict a lot of "what a load of crap" puns. Apart from dealing with diebetes perhaps this could become a health/weight loss craze. "The secret to staying thin-two girls and cup know!"

[Professor Yaffle]

Thats interesting. I've heard of it being used for treatment of C. dificile infection and ulcerative colitis, but using it for pre diabetes is new to me.

http://en.wikipedia.org/wiki/Fecal_bacteriotherapy
http://www.telegraph.co.uk/news/uknews/1570515/Grandmother-saved-by-daughters-poo.html
http://journals.lww.com/jcge/Fulltext/2010/09000/Fecal_Bacteriotherapy,_Fecal_Transplant,_and_the.8 .aspx

[Starthinker]

So all those times my ex told me to eat s*** she was just looking out for my health?

[Dr. Imago]

Yeah, it's gonna take a lot more than an 18-patient trial to convince me to feed **** to my patients.

Sorry. I'm not convinced. In fact, I don't even consider this "promising" research at this point.

~Dr. Imago

[casebro]

Is this another instance where sanitation is proving detrimental to good health?

[casebro]

But hmmmm.... there is a pretty good link of alcohol to diabetes. I sure find that the glass of wine with dinner lowers my blood sugar- I'm type II, on insulin. I know that the by-products of alcohol metabolism are the same as fat metabolism by-products- acetaldehyde. I feel that the mechanism may be that the body confuses the acetaldehyde from alcohol as a signal that the body has burned fats, and needs to boost the sugar metabolism.

Germaine to today's point could be that the 'germs' (yeast, easiest answer) in the gut make sugars into alcohol, sending a message having to do with boosting the sugar metabolism. Aren't there several studies re: alcohol consumption being good for diabetics?

I'll drink to that!

Much preferred activity over eating $__+. ;)

[casebro]

Hate to be a thread necromancer, but :

http://www.ncbi.nlm.nih.gov/pubmed/1802190

"Recent developments in short-chain fatty acid metabolism."

Basically, internal bio breaks down undigestibles, make short chain fatty acids in the colon. SCFA is good for the mucosal linings.

I think I'll go eat some coconut oil, loaded with SCFAs. Or goat's milk/cheese. ETA: The germs in the goat's digestive tract turn the cellulose into the SCFAs, no?

[C_Felix]

My question is this:
Who came up with this idea?
"Hey! I gotta idea!"
"What is it Lars?"
"Lets transplant some **** from some skinny people to some fat people!"
"(chrip) (chirp)"

[Emet]

My question is this:
Who came up with this idea?
"Hey! I gotta idea!"
"What is it Lars?"
"Lets transplant some **** from some skinny people to some fat people!"
"(chrip) (chirp)"

Actually, it has been used in veterinary medicine for some time:

The hypothesis behind fecal bacteriotherapy rests on the concept of bacterial interference: using harmless bacteria to displace pathogenic organisms. This approach to combating bacterial infections is not new[4], and has long been used in animals; for example, to prevent salmonellosis in chickens[5].

http://en.wikipedia.org/wiki/Fecal_bacteriotherapy#Theoretical_basis

[casebro]

Anecdote or History: When the Germans were in North Africa, a German Herr Doktor was puzzled by the way the Arabs didn't seem to be bothered by the Dysentery that was killing the German Soldiers. So he asked a trusted indigenous assistant. The local cure was to swallow some fresh horse dung. "harmless bacteria to displace pathogenic organisms. "

Related to this thread, I have been looking into SCFA, short chain fatty acids. Seems the intestinal flora feed on un-digestible fiber, making SCFAs, used directly by the intestinal mucosa to heal themselves. I have a mitochondrial disease, and seem to do better with higher intakes of SCFAs. Not doing as well lately, since I cut back on food fried in coconut oil, and butter. So now I'm back on to oatmeal pancakes fried in coconut oil, slathered in butter.

There is much googlable on SCFAs linked to diabetes. I have diabetes too, and one study showed about 17% of diabetics have a mito gene prob. Mitos prefer SCFAs as fuel, and folks with problems may lack the enzyme to break long chains. So short chains it is for me, not just my myopathy, but for my diabetes.

So: germs make more SCFAs in the intestines, good for the intestines AND diabetes in general?