View Full Version : Cloned kitties
crimresearch
12th October 2004, 03:11 PM
http://www.msnbc.msn.com/id/6226605/
"...A dog, which Hawthorne said was the most difficult species to clone, was expected during the first quarter of 2005."
Cloned sheep...cats...dogs...
Can cloned politicians be far behind?
Darat
12th October 2004, 03:32 PM
Originally posted by crimresearch
http://www.msnbc.msn.com/id/6226605/
"...A dog, which Hawthorne said was the most difficult species to clone, was expected during the first quarter of 2005."
Cloned sheep...cats...dogs...
Can cloned politicians be far behind?
I thought they'd been working "upwards" so to speak in terms of complexities? I'd always assumed they'd cracked politicians before slime moulds...
At a loss for why you would want to clone a cat. Come to think of it I can see why, cats are so variable in colouring and patterns then it could be the only way to guarantee a specific mix again. But then I wonder how “identical" it would be considering gestation and then diet, upbringing and so on. I can see “major” features being preserved (such as eye colouration) but would the fine detail of say a tabby’s stripes or a tortoiseshell’s splodges be identical?
Hellbound
12th October 2004, 04:22 PM
Originally posted by Darat
I thought they'd been working "upwards" so to speak in terms of complexities? I'd always assumed they'd cracked politicians before slime moulds...
At a loss for why you would want to clone a cat. Come to think of it I can see why, cats are so variable in colouring and patterns then it could be the only way to guarantee a specific mix again. But then I wonder how “identical" it would be considering gestation and then diet, upbringing and so on. I can see “major” features being preserved (such as eye colouration) but would the fine detail of say a tabby’s stripes or a tortoiseshell’s splodges be identical?
Do a google search for "CC clone kitten". They cloned this calico, and although genetically identical, it's coloration was completely different from its "mother". It's speculated that conditions in the womb determine color for calicos...it's probably similar for other types.
Edited to provide a better search term and fix sum spaleing airers.
Crossbow
12th October 2004, 05:42 PM
Originally posted by crimresearch
http://www.msnbc.msn.com/id/6226605/
"...A dog, which Hawthorne said was the most difficult species to clone, was expected during the first quarter of 2005."
Cloned sheep...cats...dogs...
Can cloned politicians be far behind?
It has already been done!
Did you not see the movie The Boys From Brazil?
:p
Darat
13th October 2004, 02:36 AM
Originally posted by Huntsman
Do a google search for "CC clone kitten". They cloned this calico, and although genetically identical, it's coloration was completely different from its "mother". It's speculated that conditions in the womb determine color for calicos...it's probably similar for other types.
Edited to provide a better search term and fix sum spaleing airers.
Thanks for that. So it looks as if "Clone-A-Pet" is going to have a lot of disappointed customers.
Store Clerk: "Here's your kitten."
Customer: "No it isn't, Kitty had orange splodges on his ears"
Store Clerk: "Here's the "Clone Check" paperwork, this is a guaranteed 100% genetically identical clone of Kitty."
Customer: "But I wanted Kitty back!"
Store Clerk: "You know when you took Kitty to the vets for her last visit?"
Customer: "Yes..."
Store Clerk: "Which part of "I'm sorry but Kitty is dead." didn't you understand?"
Rolfe
13th October 2004, 05:03 AM
Sitting here reading an article about cloned kittens in today's Veterinary Times."It's a very exciting result," said Lou Hawthorne. "These two remarkable kittens should finally put to rest the issue of resemblance between clones and their genetic donors. When performed by a skilled team using sufficiently advanced technology, clones resemble their donors to an uncanny degree - just as we predicted. It's a happy day for outr clients."
"Our first attempts using the new CT cloning technology were very successful," said GSC chief scientific officer Dr Irina Polejaeva, "which suggests that the new method is everything we hoped it would be."
Chromatin transfer (CT) involves pre-treating the cell of the animal to be cloned to remove molecules associated with cellular differentiation. The technology is more advanced than nuclear transfer (NT), the method used to clone Dolly the sheep and most other animal clones. CT has been shown in various animal studies to be more efficient than NT, and to result in healthier animals. GSC holds an exclusive licence to use CT for cloning pets.Now this article is a bit of a puff piece, so has to be taken with a bit of a health warning. And the two kittens in question (aw....) are Bengals, which are spotted tabby patterned. The pattern of these markings tends to be very similar from one individual to another anyway. They look like peas in a pod, but then so do littermate tabby-patterend kittens, quite often. I'd be more impressed if I saw it done with some sort of piebald or skewbald/tortoiseshell patterning, which can vary in pattern quite a lot.
The kittens will be exhibited at cat shows, but as they are in California, probably only in the States. If they got them Pet Passports and brought them over here, I'd certainly turn up to take a look. (in fact, I'd fight to get to vet-in at the show, dammit!)
Rolfe.
Gestahl
13th October 2004, 12:12 PM
Originally posted by Huntsman
Do a google search for "CC clone kitten". They cloned this calico, and although genetically identical, it's coloration was completely different from its "mother". It's speculated that conditions in the womb determine color for calicos...it's probably similar for other types.
Huntsman,
I could be wrong, but calico coloration is due to a gene on the X chromosome. In many mammals (including humans) one of the X chromosomes in every female's cell is deactivated in a semi-random fashion (daughter cells tend to have the same X chomosome deactivated as the mother cell). Which one is deactivated determines which coat color is expressed (along with secondary genes that determine the base color). They should have the same colors, just differently located "splotches".
Wikipedia has a pretty indepth article on cat coloration genetics here (http://en.wikipedia.org/wiki/Cat_coat_genetics). Corrections are always welcomed (looking at you Rolfe).
Hellbound
13th October 2004, 02:02 PM
Originally posted by Gestahl
Huntsman,
I could be wrong, but calico coloration is due to a gene on the X chromosome. In many mammals (including humans) one of the X chromosomes in every female's cell is deactivated in a semi-random fashion (daughter cells tend to have the same X chomosome deactivated as the mother cell). Which one is deactivated determines which coat color is expressed (along with secondary genes that determine the base color). They should have the same colors, just differently located "splotches".
Wikipedia has a pretty indepth article on cat coloration genetics here (http://en.wikipedia.org/wiki/Cat_coat_genetics). Corrections are always welcomed (looking at you Rolfe).
Well, yes, both are similarly colored calicos, but the patterns are different. I was shorthanding the description, assuming that more information could be obtained from links. My fault, I was unclear :)
I didn't know the exact mechanism, btw, but initially the theories put forth had to do with conditions in the womb. The genetic marker one is new to me...I'll have to look into it. Admittedly, though, I haven't kept track of the story :)
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