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#1 |
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Critical Thinker
Join Date: Nov 2001
Location: Calgary, AB, GWN
Posts: 397
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EMF and Protein changes?
So, I'm seeing this study posted on a relative's FaceBook, and it looks like typical "OMG CELL PHONES ARE RADIOACTIVE" nonsense, but then I follow the link and it looks to my untrained eyes like they did a legit study. Could someone with better training take a peek at this and let me know if it's BS, and if so, generally why?
"Electromagnetic Biology and Medicine" Heck, is "Electromagnetic Biology and Medicine" even a legit journal? It sure sounds hokey. The FB article linked was actually this very cheesy looking site. Thanks, Jason |
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#2 |
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Penultimate Amazing
Join Date: Jul 2006
Posts: 13,418
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To save others the search, the complete paper is available here for free:
http://media.withtank.com/cac3770262...et_al-2012.pdf Not my field of expertise (not even close ) so the only point I'll make is that the sample size is rather small.
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"Reality is what's left when you cease to believe." Philip K. Dick |
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#3 |
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Scatterer of X-rays
Join Date: Aug 2007
Location: Oxfordshire
Posts: 742
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It appears to be a legitimate journal, but only just.
Web of Science shows it has an impact factor (citations per article) of 1.04. To put that in context, the journal is listed in two categories: Biology, where it is 55th out of 86 journals Biophysics, where it is 61st out of 73 journals It's either a place to publish incredibly specialised work, or a journal of last resort for work that can't get in anywhere else. |
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#4 |
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Scholar
Join Date: Mar 2010
Location: Blackstone River Valley, MA
Posts: 104
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While I'm certainly no expert on biology I did spot one problem with the study that I've also seen in similar studies. They used actual cell phones and cordless base stations for the RF sources. They should be using standards based calibrated RF signal generators, amplifiers and antennas. Using manufactured consumer products instead leaves open the possibility that the mice where affected by other factors than the RF signal.
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#5 |
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Mad Scientist
Join Date: Jul 2003
Location: Alberta
Posts: 13,894
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I think we did a podcast on EMR...Legion of Reason
I wrote this in response to some people trying to ban wifi in schools here: Wifi cannot cause cancer, and WHO stipulates: Considering the very low exposure levels and research results collected to date, there is no convincing scientific evidence that the weak RF signals from base stations and wireless networks cause adverse health effects. /quote http://www.who.int/mediacentre/facts.../en/index.html Physicists can explain why: http://bobpark.physics.umd.edu/WN12/wn031312.html http://bobpark.physics.umd.edu/WN08/wn072508.html Einstein won the 1905 Nobel Prize in Physics for showing that cell phones can't cause cancer. The threshold energy of the photoelectric effect, for which Einstein won the prize, lies at the extreme blue end of the visible spectrum in the near ultraviolet. The same near-ultraviolet rays can also cause skin cancer. Red light is too weak to cause cancer. Cell-phone radiation is 10,000 times weaker. -This goes for WiFi too. http://www.australianscience.com.au/...-human-health/ In fact, due to their lower frequency, at similar RF exposure levels, the body absorbs up to five times more of the signal from FM radio and television than from base stations./quote And most of the "experts" listed at the link she sent are Chiros!! NOT a good site, and should be dismissed based on their "about us": http://www.safeschool.ca/About_Us.html One person (not a physicist) claims their kid is sensitive to wifi, but where is the EVIDENCE? So, I guess they are getting rid of radios, computers, TVs, etc. as well? My laptop is warming my knees at the moment as I type. If it gets too hot, I know to move it. Claiming it will cause cancer is like claiming sitting in front of a wood burning fire will cause cancer. Nope... and people can tell when temperatures are getting too hot, and we do not get burned from these kinds of wavelenghts that are being emitted by cell phones, wireless, radio, etc. |
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Motion affecting a measuring device does not affect what is actually being measured, except to inaccurately measure it. the immaterial world doesn't matter, cause it ain't matter-Jeff Corey my karma ran over my dogma-vbloke The Lateral Truth: An Apostate's Bible Stories by Rebecca Bradley, read it! |
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#6 |
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Critical Thinker
Join Date: Nov 2001
Location: Calgary, AB, GWN
Posts: 397
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Thanks much. I know just enough of the theoretical side of why cell phones are about as dangerous as light bulbs to discard the concerns as 99% likely to be bunk, but tend to respect papers published in actual journals.
The site linked is, of course, total hogwash, but I was mostly interested in whether "Electromagnetic Biology and Medicine" was legit at all, or a pseudo-journal. Not anything I'm personally that concerned about. If my cell phone isn't sitting next to my head, it's in my front pocket. I'll let you folks know if I start going all Bruce Banner.
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#7 |
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Muse
Join Date: Aug 2005
Location: Elk Grove, California
Posts: 851
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This is an area where I think self-described skeptics are concluding far too aggressively. Anyone with a real interest in this topic should spend considerable time chasing the references listed in this article. If the article is correct, then there's plenty of literature indicating that exposure to some electromagnetic radiation may cause some biochemical changes.
We should not rely on theory to discard empirical data, but that's what we do when we argue that something cannot be true based on current theory. It's not good science. It's not good thinking. It's not good for anything other than reinforcing preexisting assumptions. |
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“Science is an integral part of culture. It's not this foreign thing, done by an arcane priesthood. It's one of the glories of the human intellectual tradition.” - Stephen Jay Gould |
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#8 |
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Neo-Post-Retro-Revivalist
Join Date: Aug 2005
Location: The Emerald City
Posts: 7,958
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"All opinions are not equal. Some are a very great deal more robust, sophisticated and well supported in logic and argument than others." -- Douglas Adams "The absence of evidence might indeed not be evidence of absence, but it's a pretty good start." -- PhantomWolf "Let's see the buggers figure that one out." - John Lennon |
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#9 |
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red-shirted crewman
Join Date: Jul 2004
Location: Ontario, Canada
Posts: 1,641
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The anti-wifi groups seem to have given up on the Cancer angle these days, and instead are concetrating on these studies that appear to show that wifi can cause some kind of unspecified "biochemical changes." There is no indication that these alleged "biochemical changes" have any detrimental effect whatsoever, but the wifi wingnuts insist on employing the scaremongering tactics of claiming that they "might". So we should shut down all of western civilisation, just in case...
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Aurora Walking Vacation "A point of view can be a dangerous luxury when substituted for insight and understanding."--Marshall McLuhan |
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#10 |
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Graduate Poster
Join Date: Jun 2004
Location: The Ancient Isle of Avignuon
Posts: 1,074
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__________________
"The test of democracy is freedom of criticism." -David Ben-Gurion Peasant: Now we see the violence inherent in the system. King: Shut up! Peasant: Come and see the violence inherent in the system, help, help! I’m being repressed! King: Bloody peasant! Peasant: Ooh, what a giveaway, did you hear that... that’s what I’m on about, d’you see him repressing me? You saw it didn’t you... - Monty Python and The Holy Grail |
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#11 |
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Graduate Poster
Join Date: Jun 2004
Location: The Ancient Isle of Avignuon
Posts: 1,074
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I hadn't realised that - it's pathetic really. Just like the anti vaccers deciding that even if vaccines don't cause autism they must cause something else instead because they are BAAAAD!
I like the phrase 'wifi wingnuts' and I'm going to use it whenever an opportunity presents itself ![]() Yuri |
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"The test of democracy is freedom of criticism." -David Ben-Gurion Peasant: Now we see the violence inherent in the system. King: Shut up! Peasant: Come and see the violence inherent in the system, help, help! I’m being repressed! King: Bloody peasant! Peasant: Ooh, what a giveaway, did you hear that... that’s what I’m on about, d’you see him repressing me? You saw it didn’t you... - Monty Python and The Holy Grail |
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#12 |
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Muse
Join Date: Aug 2005
Location: Elk Grove, California
Posts: 851
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With all due respect, I wish you would read the actual article about which this thread was posted and then re-read my response. The paper summarizes a great deal of peer reviewed, empirical research that indicates electromagnetic radiation may cause some biochemical change. Dismissing these data because they do not fit our current theoretical understanding is not skeptical. It's lazy.
I'm going to quote directly from the article:
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So from where does your confidence come? You can't possibly read this introduction with a skeptical, open mind that respects the scientific process and conclude that this is an open and shut case-- unless you can demonstrate that all these studies were flawed or that this entire paper is an outright fraud. And sure, maybe they are. Maybe it is. But if that's your contention, demonstrate it. My general rule of thumb is that if serious scientists produce serious research published in serious scientific journals, I'm probably not in a position to argue against their results. My beef isn't with WIFI or cell phones; I use a cell phone and I'm typing at my WIFI computer. My beef is with the disrespect of the scientific process that occurs when non-scientists pound their chests, stick flags in the ground, and proclaim absolute confidence regarding topics of which they have an arm-chair-analyst understanding and about which serious researchers are still uncertain. |
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“Science is an integral part of culture. It's not this foreign thing, done by an arcane priesthood. It's one of the glories of the human intellectual tradition.” - Stephen Jay Gould |
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#13 |
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Graduate Poster
Join Date: Jun 2004
Location: The Ancient Isle of Avignuon
Posts: 1,074
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OK, now you need to find out what 'burden of proof' means as well as the difference between ionizing and non-ionizing radiation
.All available evidence suggests that non-ionizing radiation cannot cause the DNA mutations necessary to cause cancers, the epidemiology suggests there is no link between mobile phone use and brain cancer and even if mobile phones did cause cancer we would be seeing an epidemic of skin, not brain cancers as skin is a far more active, labile tissue than brain. In short the overwhelming evidence is that mobile phones cannot and do not cause cancer. Therefore the 'burden of proof' is for those claiming otherwise to prove their case satisfactorily, not for anyone else to 'disprove' studies which make such claims. It is not necessary to give a detailed refutation of every paper which comes up with conclusions which fly in the face of the overwhelming concensus on any one subject. This is where the 'confidence' comes from. The text you have quoted has a lot of insinuations and inferences but when they say stuff like: "They... concluded that EMF exposure caused distinct effects on gene and protein expression" and: "protein expression changes might depend on duration and mode of exposure and therefore a number of biological processes might be affected" without saying what 'effects' they mean, and: "mobile phone radiation might alter protein expression in human skin cells" "Gene expression changes as revealed using transcriptomics had not [sic] effects on... mouse cells. However... such a limited and non systematic number of publications using “omics” approaches does not allow for any conclusions to be drawn concerning the impact of mobile phone emitted radiation upon cell proteome, physiology and function" and: "Concerning research on wireless DECT base and handset radiation exposure which is potentially harmful to millions of people" I'm afraid it's got 'agenda driven', 'scare mongering', 'unscientific language' and 'weaselly qualifiers' written all over it. You are suggesting anyone who treats this paper with scepticism is narrow minded; I would suggest that you give people the benefit of the doubt. Many of us have "been here before" with the "ground breaking, paradigm-shifting, establishment rocking paper" scenario, whether it refers to EMF, homeopathy, creationism, etc etc etc... or whatever. This is just more of the same. Maybe once a few more different people come up with the same conclusion, once the studies are replicated and once they stop trying to squeeze as many hints and inferences out of the data which suit their pre-conceptions as possible then some of the people here might think it was worth a more serious look. Cheers ,Yuri |
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"The test of democracy is freedom of criticism." -David Ben-Gurion Peasant: Now we see the violence inherent in the system. King: Shut up! Peasant: Come and see the violence inherent in the system, help, help! I’m being repressed! King: Bloody peasant! Peasant: Ooh, what a giveaway, did you hear that... that’s what I’m on about, d’you see him repressing me? You saw it didn’t you... - Monty Python and The Holy Grail |
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#14 |
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Muse
Join Date: Aug 2005
Location: Elk Grove, California
Posts: 851
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Burden of proof?
Stop for a minute. Think this through. Researchers are simply reporting results from experiments. The methodologies and results have been accepted by and published in peer-reviewed journals. You are discarding the results. You are ignoring the data. Who has the burden of proof here?
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My understanding is that epidemological data clearly indicate that acute exposure to cell phone radiation does not cause cancer. Chronic exposure data, however, are lacking. Increased cancer risk was noted in the highest exposure group (30 minutes a day for 10 years) of the INTERPHONE study. Other studies have also indicated increased risk associated with exposures greater than 10 years (e.g., http://www.ncbi.nlm.nih.gov/pmc/arti...tool=pmcentrez). But these data are scant, so firm conclusions cannot be drawn. No matter, the International Agency on the Research of Cancer of the World Health Organization "has classified radiofrequency electromagnetic fields as possibly carcinogenic to humans (Group 2B), based on an increased risk for glioma, a malignant type of brain cancer, associated with wireless phone use" (http://www.iarc.fr/en/media-centre/p...fs/pr208_E.pdf). If the epidemological data are uncertain enough for WHO to admit a potential link, I would suggest my posts here in defense of uncertainty are rather benign (get it?). Finally, I have not argued that cell phones cause cancer. In my brief reading of the article lined in the OP, I did not see claims that cell phones cause cancer. In my brief reading, I saw a quick review of literature indicating that electromagnetic radiation can cause some biochemical changes and some new published data that seem to bolster previous findings. In my brief reading of responses here, I saw multiple posters discarding this article simply because "non-ionizing radiation cannot cause cancer." I saw no serious review of the literature. I saw no honest discussion of potential uncertainty.
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I don't understand how carefully acknowledging the uncertain nature of current data can be considered "scare mongering."
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I am suggesting laziness of those who discard this paper without bothering to read it and assess the wealth of referenced research that bolster its claims. And it's not just that I'm claiming laziness. It is lazy. Discarding data just because they challenge your current worldview is lazy. It is not skeptical. It's cynical. And lazy.
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“Science is an integral part of culture. It's not this foreign thing, done by an arcane priesthood. It's one of the glories of the human intellectual tradition.” - Stephen Jay Gould |
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#15 |
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Graduate Poster
Join Date: Feb 2009
Posts: 1,224
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That was very, very well said. It's like a fresh breath of air. I wish more people would take what you said to heart.
Skeptic: one who is yet undecided as to what is true; one who is looking or inquiring for what is true; an inquirer after facts or reasons. the method of suspended judgment, systematic doubt, or criticism that is characteristic of skeptics Debunker – one who holds an a priori belief that it does not exist, therefore, it is just a matter of finding a way to explain it away. Debunkers cloak denialism in the language of skepticism and critical thinking. They start with a negative conclusion and look for evidence to support what they already believe. “It can’t exist, therefore, it doesn’t exist.” When it comes to any topic that falls under the heading of 'woo', I see too much of one and not enough of the other. |
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Occam’s Beard – The simplest solution isn’t always the best |
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#16 |
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Graduate Poster
Join Date: Jun 2004
Location: The Ancient Isle of Avignuon
Posts: 1,074
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![]() So anything in a "peer reviewed" journal is above criticism? Like I said, the people who think non-ionising radiation can cause cancer. "May challenge" what does that mean? - what empirical data are you talking about, where is the epidemic of skin cancers caused by mobile phones? Empirical data may prove the moon is made of cheese but it hasn't happened yet. Well, read it again:
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Sorry? how long have people been using cell phones - the ones 'yuppies' used in the 80's were massively more powerful than current phones - where is the epidemic? Hey, I think I found your dog! 'Cos that's how science works. ![]() Yuri |
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"The test of democracy is freedom of criticism." -David Ben-Gurion Peasant: Now we see the violence inherent in the system. King: Shut up! Peasant: Come and see the violence inherent in the system, help, help! I’m being repressed! King: Bloody peasant! Peasant: Ooh, what a giveaway, did you hear that... that’s what I’m on about, d’you see him repressing me? You saw it didn’t you... - Monty Python and The Holy Grail |
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#17 |
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Muse
Join Date: Mar 2006
Location: Where the jackalopes roam.
Posts: 817
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If you wish to avoid cancer, I suggest not using your cellphone outside when the Sun is shining.
V. |
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It makes sense, if you don't think about it. - T-Mobile ad You're innocent when you dream. - Tom Waits Religion was invented when the first con man met the first fool. - Samuel Clemens |
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#18 |
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Muse
Join Date: Aug 2005
Location: Elk Grove, California
Posts: 851
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I'm growing tired of silly antics used to "win" an argument. Obviously I've suggested nothing of the sort. I'd greatly appreciate you showing a little respect and not posting straw.
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Lazy.
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You are not arguing to understand. You're arguing to win. This will be my last response unless you want to have an honest discussion. I have no interest in preserving my ego. I just want to understand what these data mean. You aren't helping me. You're just wasting my time.
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Will you please concede that these studies... exist?
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You are free to demonstrate that I am wrong. You are free to demonstrate that I've misinterpreted the few studies that assess risk for those exposed for more than 10 years. You are free to demonstrate that I am ignoring numerous datasets covering more than 10 years of exposure that do not indicate increased risk. In fact, you are encouraged to do any of these things. These would be constructive demonstrations that I could use to better understand what I should conclude. But you're not doing that. You are ignoring these data and arguing straw. It's not good for you. It's not good for me. It doesn't actually change reality. It may feel good, but it makes you no less likely to be correct.
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Numerous studies have indicated similar outcomes. This study is duplicating previously reported results. I'm not sure what you think you're accomplishing here. You can type until your fingers blister, but these data still exist, and it's very difficult to understand how they could exist if our current understanding of cell phone radiation is complete. And that's where discussion should focus. You should be trying to explain why these data are unreliable, or how they should impact our current theory. But you're not. You're simply proudly ignoring them. And that's easy. And serious skeptical thinking isn't easy. When the INTERPHONE study was first published, I was confident cell phones did not cause cancer. The results of the highest use group (30 minutes a day for 10 years) did not offer confidence. In fact, they indicated an increase in risk. It wasn't easy, but I necessarily had to adjust my position to account for these data, because I am committed to evidence, not ego. While my adjustment is ridiculed by self described skeptics like you, I note that I am not alone: WHO did the same. |
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“Science is an integral part of culture. It's not this foreign thing, done by an arcane priesthood. It's one of the glories of the human intellectual tradition.” - Stephen Jay Gould |
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#19 |
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Graduate Poster
Join Date: Jun 2004
Location: The Ancient Isle of Avignuon
Posts: 1,074
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__________________
"The test of democracy is freedom of criticism." -David Ben-Gurion Peasant: Now we see the violence inherent in the system. King: Shut up! Peasant: Come and see the violence inherent in the system, help, help! I’m being repressed! King: Bloody peasant! Peasant: Ooh, what a giveaway, did you hear that... that’s what I’m on about, d’you see him repressing me? You saw it didn’t you... - Monty Python and The Holy Grail |
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#20 |
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Master baiter - I fish!
Join Date: Mar 2004
Location: Bulgaria
Posts: 967
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Unbelievable.
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#21 |
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Master Poster
Join Date: Aug 2001
Posts: 2,051
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Gene/protein expression is induced, up-regulated, down-regulated, etc. by all manner of environmental stimuli. It doesn't mean DNA damage occurs, which is the only current, known, and - most importantly - plausible mechanism of cancer formation.
I'm with Yuri on this one. ~Dr. Imago |
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DISCLAIMER: The above post is for informational and/or educational purposes only. It is not a substitute for the professional judgment of, in direct consultation with, a health care professional in diagnosing, treating, and/or preventing any disease or disorder. It is not to be construed as individualized medical advice, diagnosis, or a treatment recommendation. Your reliance upon the information obtained or used by you at, through, or as a result of this post is solely at your own risk. |
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#22 |
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Graduate Poster
Join Date: Jun 2004
Location: The Ancient Isle of Avignuon
Posts: 1,074
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Coincidentally I came across two articles today which tie in with this subject but have oodles more plausibility.
This one: - http://the-scientist.com/2012/04/10/...-brain-tumors/, about this article - http://onlinelibrary.wiley.com/doi/1...ncr.26625/full, suggests that brain tumours may be caused by dental x-rays. It's not conclusive and no one is panicking (give it time ) but at least it's plausible, x-rays being ionizing radiation, and infinitely more so than the idea that cellphone radiation causes cancer. The study though, still doesn't explain whether the incidence of tumours of the gum or facial bones is also increased by dental x-rays as would be expected, both those tissues being far more likely to develop tumours normally.The second one is an article discussing how two intracellular proteins, Rab25 and CLIC3 can, in certain circumstances act in combination to promote the development of tumours. The original paper is here. The big difference between this one and the paper in the o.p. is the complete lack of bogus attemts to link the results with any preconcieved notions, namely that cell phones cause cancer by modifying proteins. Whatever its merits, this is just a straightforward paper, without any political 'spin' or "authors' message". That's how it should be done. Yuri |
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"The test of democracy is freedom of criticism." -David Ben-Gurion Peasant: Now we see the violence inherent in the system. King: Shut up! Peasant: Come and see the violence inherent in the system, help, help! I’m being repressed! King: Bloody peasant! Peasant: Ooh, what a giveaway, did you hear that... that’s what I’m on about, d’you see him repressing me? You saw it didn’t you... - Monty Python and The Holy Grail |
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