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Tags paper , genetics , cell , sickle

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Old 26th October 2004, 05:12 PM   #1
Johnny Pneumatic
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Sickle Cell Genetics Paper

I've been so busy lately and my genetics paper for Biology has slipped up on me. My topic is Sickle Cell Anemia. I need informational sources on it, please help!
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Old 26th October 2004, 05:56 PM   #2
Dr. Imago
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Re: Sickle Cell Genetics Paper

Quote:
Originally posted by SkepticJ
I've been so busy lately and my genetics paper for Biology has slipped up on me. My topic is Sickle Cell Anemia. I need informational sources on it, please help!
What, precisely, are you looking for (i.e., what's the thesis of your paper)?

-TT
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DISCLAIMER: The above post is for informational and/or educational purposes only. It is not a substitute for the professional judgment of, in direct consultation with, a health care professional in diagnosing, treating, and/or preventing any disease or disorder. It is not to be construed as individualized medical advice, diagnosis, or a treatment recommendation. Your reliance upon the information obtained or used by you at, through, or as a result of this post is solely at your own risk.
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Old 26th October 2004, 05:58 PM   #3
geni
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Re: Sickle Cell Genetics Paper

Quote:
Originally posted by SkepticJ
I've been so busy lately and my genetics paper for Biology has slipped up on me. My topic is Sickle Cell Anemia. I need informational sources on it, please help!
well this should give you an idea what to look for

http://en.wikipedia.org/wiki/Sickle_Cell_Anemia
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Old 26th October 2004, 06:06 PM   #4
Paul C. Anagnostopoulos
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Don't forget to discuss the relation between sickle cell and malaria.

~~ Paul
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Old 27th October 2004, 01:53 AM   #5
Kumar
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You can ckeck here:http://www.nlm.nih.gov/medlineplus/s...ellanemia.html

http://www.google.com/search?hl=en&i...=Google+Search
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Old 27th October 2004, 07:12 AM   #6
Soapy Sam
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http://www.innvista.com/health/ailme...s/sickhist.htm

Paul is right. Anthony Allison had , I believe, lived in East Africa. He suspected that the distribution of SCA was related to malaria.
It appears that the mutation responsible for SCA confers resistance to malaria and so could spread through west Africa although itself a harmful mutation. Among descendants of west African slaves in the US, the condition has no positive benefit , while retaining it's negative effects.

Check out Thalassaemia too- another form of amaemia, widespread around the eastern Mediterranean. It seems to confer similar resistance to malaria.

It seems probable that many other human genes have evolved in response to selective pressure from malaria and other endemic disease. The SCA mutation is just a good example .
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