Drug Trial Fiasco

Badly Shaved Monkey · 16th March 2006, 01:32 AM

http://news.bbc.co.uk/1/hi/england/london/4807042.stm

Doeas anyone have a suggestion as to what class of drug they may have been testing? There is no clear indication in the public press stories. The reaction seems to have been so extreme my first thought is that there is more likely to have been a cock-up in the manufacture and they were given something really nasty by mistake rather than it being a reaction to the intended drug molecule. Even so, such a bad reaction from milligramme quantities of anything is fairly scary.

Capsid · 16th March 2006, 01:35 AM

See this thread BSM.

Its an anti-CD28 humanised monclonal antibody.

Badly Shaved Monkey · 16th March 2006, 01:48 AM

Thanks. I'd looked for a thread before I posted and didn't spot your one.

Since it was an Ab I can more easily see why it could cause a calamitous generalised effect without needing contamination.

16th March 2006, 01:32 AM	#1
Badly Shaved Monkey Anti-homeopathy illuminati member Join Date: Feb 2004 Location: Outside a banana and far from a razor Posts: 5,262	Drug Trial Fiasco http://news.bbc.co.uk/1/hi/england/london/4807042.stm Doeas anyone have a suggestion as to what class of drug they may have been testing? There is no clear indication in the public press stories. The reaction seems to have been so extreme my first thought is that there is more likely to have been a cock-up in the manufacture and they were given something really nasty by mistake rather than it being a reaction to the intended drug molecule. Even so, such a bad reaction from milligramme quantities of anything is fairly scary.
	__________________ "i'm frankly surprised homeopathy does as well as placebo" Anonymous homeopath. "Alas, to wear the mantle of Galileo it is not enough that you be persecuted by an unkind establishment; you must also be right." (Robert Park) Is the pen is mightier than the sword? Its effectiveness as a weapon is certainly enhanced if it is sharpened properly and poked in the eye of your opponent.

16th March 2006, 01:35 AM	#2
Capsid Graduate Poster Join Date: Apr 2004 Posts: 1,506	See this thread BSM. Its an anti-CD28 humanised monclonal antibody.
Capsid Graduate Poster Join Date: Apr 2004 Posts: 1,506

16th March 2006, 01:48 AM	#3
Badly Shaved Monkey Anti-homeopathy illuminati member Join Date: Feb 2004 Location: Outside a banana and far from a razor Posts: 5,262	Thanks. I'd looked for a thread before I posted and didn't spot your one. Since it was an Ab I can more easily see why it could cause a calamitous generalised effect without needing contamination.
	__________________ "i'm frankly surprised homeopathy does as well as placebo" Anonymous homeopath. "Alas, to wear the mantle of Galileo it is not enough that you be persecuted by an unkind establishment; you must also be right." (Robert Park) Is the pen is mightier than the sword? Its effectiveness as a weapon is certainly enhanced if it is sharpened properly and poked in the eye of your opponent.